Rabbit Monoclonal Antibody to Clusterin

Clusterin (CLU, apolipoprotein J) is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress~induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer’s disease by sequestering amyloid β(1~40) peptides to form long~lived, stable complexes, which prevents amyloid fibril formation.