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Rabbit Monoclonal Antibody to PHD2 / prolyl hydroxylase
-
货号：
55113 -
别名：
EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM~20; SM20; ZMYND6; -
应用：
WB IP -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q9GZT9 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to PHD2 / prolyl hydroxylase
Description |
|---|
Catalyzes the post~translational formation of 4~hydroxyproline in hypoxia~inducible factor (HIF) alpha proteins. Hydroxylates HIF~1 alpha at 'Pro~402' and 'Pro~564', and HIF~2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel~Lindau ubiquitination complex. |
Specification |
|
|---|---|
| Aliases | EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM~20; SM20; ZMYND6; |
| Swissprot | Q9GZT9 |
| clone | 4F4E4 |
| WB Predicted band size | 46kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human PHD2 / prolyl hydroxylase |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IP | 1/50 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#55113
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