Rabbit Monoclonal Antibody to MBD1

Description
Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7~mG that is produced by DNA damage by methylmethanesulfonate (MMS).

Specification
Aliases	CXXC 3; Mbd1; MECP1 COMPLEX; PCM1; RFT;
Swissprot	Q9UIS9
clone	4H6F2
WB Predicted band size	67kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human MBD1
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/1000
IP	1/20
IHC	1/50~1/200
IF/ICC	1/50~1/200