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Rabbit Monoclonal Antibody to Drosha
-
货号:
55036 -
别名:
Ribonuclease 3 (EC:3.1.26.3); Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3; RNASE3L; RNASEN; -
应用:
WB IHC IF FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q9NRR4 -
规格:
-
数量:
-+ -
说明书:
目录价¥1280
Rabbit Monoclonal Antibody to Drosha
Description |
|---|
Drosha was identified as a nuclear RNase III that catalyzes the initial step of microRNA (miRNA) processing. This enzyme processes the long primary transcript pri~miRNAs into stem~looped pre~miRNAs. Interference of Drosha results in the increase of pri~miRNAs and the decrease of pre~miRNAs. Drosha exists in a multiprotein complex called Microprocessor along with other components such as DGCR8. Drosha, along with DGCR8, is necessary for miRNA biogenesis. |
Specification |
|
|---|---|
| Aliases | Ribonuclease 3 (EC:3.1.26.3); Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3; RNASE3L; RNASEN; |
| Swissprot | Q9NRR4 |
| clone | 7E5H5 |
| WB Predicted band size | 159kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Drosha |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000~1/5000 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
| FCM | 1/50 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#55036
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