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Rabbit Monoclonal Antibody to Drosha
Rabbit Monoclonal Antibody to Drosha

Rabbit Monoclonal Antibody to Drosha

  • 货号:

    55036
  • 别名:

    Ribonuclease 3 (EC:3.1.26.3); Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3; RNASE3L; RNASEN;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9NRR4
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to Drosha

Description

Drosha was identified as a nuclear RNase III that catalyzes the initial step of microRNA (miRNA) processing. This enzyme processes the long primary transcript pri~miRNAs into stem~looped pre~miRNAs. Interference of Drosha results in the increase of pri~miRNAs and the decrease of pre~miRNAs. Drosha exists in a multiprotein complex called Microprocessor along with other components such as DGCR8. Drosha, along with DGCR8, is necessary for miRNA biogenesis.

Specification

Aliases Ribonuclease 3 (EC:3.1.26.3); Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3; RNASE3L; RNASEN;
Swissprot Q9NRR4
clone 7E5H5
WB Predicted band size 159kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Drosha
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/1000~1/5000
IHC 1/50~1/200
IF/ICC 1/50~1/200
FCM 1/50

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#55036