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Rabbit Monoclonal Antibody to TNF Receptor II
Rabbit Monoclonal Antibody to TNF Receptor II

Rabbit Monoclonal Antibody to TNF Receptor II

  • 货号:

    54998
  • 别名:

    CD120b; p75 TNF receptor; p80 TNF alpha receptor; Soluble TNFR1B variant 1; TBP~2; TBPII; TNF R75; TNFBR; TNFR~II; TNFR1B; TNFR2; TNFR80; TNFRII; Tnfrsf1b;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF IP FCM
  • 反应种属:

    Human Mouse Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P20333
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to TNF Receptor II

Description

Receptor with high affinity for TNFSF2/TNF~alpha and approximately 5~fold lower affinity for homotrimeric TNFSF1/lymphotoxin~alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF~alpha. Isoform 2 blocks TNF~alpha~induced apoptosis, which suggests that it regulates TNF~alpha function by antagonizing its biological activity.

Specification

Aliases CD120b; p75 TNF receptor; p80 TNF alpha receptor; Soluble TNFR1B variant 1; TBP~2; TBPII; TNF R75; TNFBR; TNFR~II; TNFR1B; TNFR2; TNFR80; TNFRII; Tnfrsf1b;
Swissprot P20333
clone 10G10H10
WB Predicted band size 73kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human Mouse Rat
Immunogen A synthesized peptide derived from human TNF Receptor II
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/500~1/2000
IP 1/50
IHC 1/50~1/200
IF/ICC 1/50~1/200
FCM 1/50

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#54998