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Rabbit Monoclonal Antibody to ADAM17
-
货号:
54935 -
别名:
CD156b; ADAM17; CSVP; TACE; -
应用:
WB IF IP FCM -
反应种属:
Human Mouse Rat -
抗体类型:
Primary antibody -
Swissprot:
P78536 -
规格:
-
数量:
-+ -
说明书:
目录价¥1280
Rabbit Monoclonal Antibody to ADAM17
Description |
|---|
TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF~α. Some tumors have hyperactivated EGFR due to upregulated TNF~α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand~independent manner and has been shown to play a role in the development of the Drosophila nervous system. |
Specification |
|
|---|---|
| Aliases | CD156b; ADAM17; CSVP; TACE; |
| Swissprot | P78536 |
| clone | 1G7C8 |
| WB Predicted band size | 100kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse Rat |
| Immunogen | A synthesized peptide derived from human ADAM17 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IP | 1/50 |
| IF/ICC | 1/50~1/200 |
| FCM | 1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54935
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