Rabbit Monoclonal Antibody to Phospho~mTOR (S2481)

Description
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell~cycle arrest and immunosuppressive effects of the FKBP12~rapamycin complex.

Specification
Aliases	FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;
Swissprot	P42345
clone	1C2H5
WB Predicted band size	289kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human Phospho~mTOR (S2481)
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000