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Rabbit Monoclonal Antibody to HDAC6
-
货号：
54812 -
别名：
HD 6; HDAC 6; Histone deacetylase 6 (HD6); JM 21; -
应用：
WB IHC IF IP -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q9UBN7 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to HDAC6
Description |
|---|
Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly~ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases. |
Specification |
|
|---|---|
| Aliases | HD 6; HDAC 6; Histone deacetylase 6 (HD6); JM 21; |
| Swissprot | Q9UBN7 |
| clone | 9B6A8 |
| WB Predicted band size | 160kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human HDAC6 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/5000~1/20000 |
| IP | 1/50 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/100~1/500 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54812
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