Rabbit Monoclonal Antibody to RUNX2

Description
RUNX2 regulates the transcription of various genes, including osteopontin, bone sialoprotein, and osteocalcin, via binding to the core site of the enhancers or promoters. RUNX2 is crucial for the maturation of osteoblasts and both intramembranous and endochondral ossification.

Specification
Aliases	Runt~related transcription factor 2; Acute myeloid leukemia 3 protein; Core~binding factor subunit alpha~1; CBF~alpha~1; Oncogene AML~3; Osteoblast~specific transcription factor 2; OSF~2; Polyomavirus enhancer~binding protein 2 alpha A subunit; CBFA1; CCD1; PEBP2aA;
Swissprot	Q13950
clone	4B2C1
WB Predicted band size	56kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human RUNX2
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
IHC	1/100~1/500
IF/ICC	1/50~1/200