Rabbit Monoclonal Antibody to IRS1

Description
IRS1 is one of the major substrates of the insulin receptor kinase. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3~kinase p85 subunit or GRB2.

Specification
Aliases	HIRS1; Insulin receptor substrate 1; IRS 1; IRS1;
Swissprot	P35568
clone	3E10C2
WB Predicted band size	170kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human IRS1
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/1000~1/2000
IHC	1/50~1/200
IF/ICC	1/50~1/200