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Rabbit Monoclonal Antibody to PRP19
-
货号：
54717 -
别名：
NMP200; nuclear matrix protein 200; pre~mRNA~processing factor 19; PRP19; PRP19/PSO4; PRPF19; PSO4; senescence evasion factor; SNEV; UBOX4; -
应用：
WB IHC IF FCM -
反应种属：
Human Mouse Rat -
抗体类型：
Primary antibody -
Swissprot：
Q9UMS4 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to PRP19
Description |
|---|
Ubiquitin~protein ligase which is a core component of several complexes mainly involved pre~mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys~63'~linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri~snRNP spliceosomal complex (PubMed:20595234). |
Specification |
|
|---|---|
| Aliases | NMP200; nuclear matrix protein 200; pre~mRNA~processing factor 19; PRP19; PRP19/PSO4; PRPF19; PSO4; senescence evasion factor; SNEV; UBOX4; |
| Swissprot | Q9UMS4 |
| clone | 2H8A2 |
| WB Predicted band size | 55kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse Rat |
| Immunogen | A synthesized peptide derived from human PRP19 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
| FCM | 1/50 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54717
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