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Rabbit Monoclonal Antibody to EEA1
-
货号：
54671 -
别名：
Early endosome antigen 1; EEA1; MST105; ZFYVE2; -
应用：
WB IF -
反应种属：
Human Mouse Rat -
抗体类型：
Primary antibody -
Swissprot：
Q15075 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to EEA1
Description |
|---|
EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1~2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol~3~phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4~6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7). |
Specification |
|
|---|---|
| Aliases | Early endosome antigen 1; EEA1; MST105; ZFYVE2; |
| Swissprot | Q15075 |
| clone | 5B4F10 |
| WB Predicted band size | 170kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse Rat |
| Immunogen | A synthesized peptide derived from human EEA1 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54671
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sales@promab.cn -
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