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Rabbit Monoclonal Antibody to M6PR
Rabbit Monoclonal Antibody to M6PR

Rabbit Monoclonal Antibody to M6PR

  • 货号:

    54660
  • 别名:

    IGF2R; CI Man~6~P receptor; CI~MPR; M6PR; MPR 300; Insulin~like growth factor 2 receptor; M6P/IGF2R; CD222;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF IP FCM
  • 反应种属:

    Human Mouse Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P11717
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to M6PR

Description

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose~6~phosphate receptors in the Golgi apparatus and the resulting receptor~ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T~cell coactivation, by binding DPP4.

Specification

Aliases IGF2R; CI Man~6~P receptor; CI~MPR; M6PR; MPR 300; Insulin~like growth factor 2 receptor; M6P/IGF2R; CD222;
Swissprot P11717
clone 8F1A9
WB Predicted band size 274kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human Mouse Rat
Immunogen A synthesized peptide derived from human M6PR
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/5000~1/20000
IP 1/30
IHC 1/50~1/200
IF/ICC 1/50~1/200
FCM 1/100

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#54660