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Rabbit Monoclonal Antibody to CXCR4
Rabbit Monoclonal Antibody to CXCR4

Rabbit Monoclonal Antibody to CXCR4

  • 货号:

    54620
  • 别名:

    CD184 ; CXCR4; C~X~C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF~1 receptor; Stromal cell~ derived factor 1 receptor;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF
  • 反应种属:

    Human Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P61073
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to CXCR4

Description

Receptor for the C~X~C chemokine CXCL12/SDF~1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

Specification

Aliases CD184 ; CXCR4; C~X~C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF~1 receptor; Stromal cell~ derived factor 1 receptor;
Swissprot P61073
clone 8E9H4
WB Predicted band size 43kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human Mouse
Immunogen A synthesized peptide derived from human CXCR4
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/100~1/200
IHC 1/50~1/200
IF/ICC 1/50~1/200

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#54620