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Rabbit Monoclonal Antibody to LGR5/GPR49
-
货号：
54619 -
别名：
FEX; GPR49; GPR67; GRP49; LGR5; HG38;8 -
应用：
WB IP FCM -
反应种属：
Human Mouse Rat -
抗体类型：
Primary antibody -
Swissprot：
O75473 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to LGR5/GPR49
Description |
|---|
Receptor for R~spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R~spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. |
Specification |
|
|---|---|
| Aliases | FEX; GPR49; GPR67; GRP49; LGR5; HG38;8 |
| Swissprot | O75473 |
| clone | 6B3A7 |
| WB Predicted band size | 100kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse Rat |
| Immunogen | A synthesized peptide derived from human LGR5/GPR49 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IP | 1/50 |
| FCM | 1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54619
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