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Rabbit Monoclonal Antibody to CD45
Rabbit Monoclonal Antibody to CD45

Rabbit Monoclonal Antibody to CD45

  • 货号:

    54599
  • 别名:

    CD45; B220; GP180; LCA; PTPRC; T200 leukocyte common antigen;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P08575
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to CD45

Description

Protein tyrosine~protein phosphatase required for T~cell activation through the antigen receptor. Acts as a positive regulator of T~cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T~cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Specification

Aliases CD45; B220; GP180; LCA; PTPRC; T200 leukocyte common antigen;
Swissprot P08575
clone 6G9A6
WB Predicted band size 150kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human CD45
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/500~1/2000
IHC 1/50~1/200
IF/ICC 1/50~1/100
FCM 1/20

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#54599