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Rabbit Monoclonal Antibody to PI 3 kinase p110 alpha
-
货号：
54576 -
别名：
PI 3 Kinase catalytic subunit alpha; phosphoinositide~3~kinase catalytic alpha polypeptide; PI3~kinase p110 alpha; PI3K; PI3K p110~alpha; PK3CA; PIK3CA; PtdIns~3~kinase p110 -
应用：
WB IF IP -
反应种属：
Human Mouse Rat -
抗体类型：
Primary antibody -
Swissprot：
P42336 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to PI 3 kinase p110 alpha
Description |
|---|
Phosphoinositide~3~kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4~phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5~bisphosphate) to generate phosphatidylinositol 3,4,5~trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain~containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. |
Specification |
|
|---|---|
| Aliases | PI 3 Kinase catalytic subunit alpha; phosphoinositide~3~kinase catalytic alpha polypeptide; PI3~kinase p110 alpha; PI3K; PI3K p110~alpha; PK3CA; PIK3CA; PtdIns~3~kinase p110 |
| Swissprot | P42336 |
| clone | 7H10F3 |
| WB Predicted band size | 110kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse Rat |
| Immunogen | A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000~1/2000 |
| IP | 1/20 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54576
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