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Rabbit Monoclonal Antibody to LRRK2
-
货号：
54563 -
别名：
Leucine~rich repeat serine/threonine~protein kinase 2; Dardarin; PARK8; ROCO2; RIPK7; LRRK2 -
应用：
WB IHC IF -
反应种属：
Human Mouse -
抗体类型：
Primary antibody -
Swissprot：
Q5S007 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to LRRK2
Description |
|---|
LRRK2 positively regulates autophagy through a calcium~dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer~dependent manner. |
Specification |
|
|---|---|
| Aliases | Leucine~rich repeat serine/threonine~protein kinase 2; Dardarin; PARK8; ROCO2; RIPK7; LRRK2 |
| Swissprot | Q5S007 |
| clone | 4A6D7 |
| WB Predicted band size | 286kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human Mouse |
| Immunogen | A synthesized peptide derived from human LRRK2 |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/500~1/2000 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54563
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