Rabbit Monoclonal Antibody to Phospho~Smad5 (S463/465)

Description
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor~regulated SMAD (R~SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes.

Specification
Aliases	hSmad5; JV5~1 ; MADH5; SMAD5; MusMLP ;SMAD family member 5;
Swissprot	Q99717
clone	2C3D5
WB Predicted band size	58kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human Phospho~Smad5 (S463/465)
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000
IHC	1/50~1/200
IF/ICC	1/50~1/200