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Rabbit Polyclonal antibody to CD146
-
货号：
54461 -
别名：
Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma~associated antigen A32; Melanoma~associated antigen MUC18; S~endo 1 endothelial~associated antigen; CD146 -
应用：
WB IP IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P43121 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Polyclonal antibody to CD146
Description |
|---|
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
Specification |
|
|---|---|
| Aliases | Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma~associated antigen A32; Melanoma~associated antigen MUC18; S~endo 1 endothelial~associated antigen; CD146 |
| Swissprot | P43121 |
| clone | 5H1C6 |
| WB Predicted band size | ~110kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human CD146. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/2000~1/5000 |
| IP | 1/50 ~ 1/200 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54461
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