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Rabbit Polyclonal antibody to CD59
-
货号：
54434 -
别名：
CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF~20; HRF20; MAC~inhibitory protein; MAC~IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59 -
应用：
WB IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P13987 -
规格：
-
数量：
-+ -
说明书：
目录价¥1180
Rabbit Polyclonal antibody to CD59
Description |
|---|
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species~specific. Involved in signal transduction for T~cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
Specification |
|
|---|---|
| Aliases | CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF~20; HRF20; MAC~inhibitory protein; MAC~IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59 |
| Swissprot | P13987 |
| clone | 3C10F7 |
| WB Predicted band size | ~17kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human CD59. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000~1/2000 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54434
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