Mouse Monoclonal Antibody to CD106/VCAM1 (2C11)

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell~cell interactions during growth and are thought to play an important role in embryogenesis and development. VCAM~1 (vascular cell adhesion molecule~1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL~1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) ~like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism