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Rabbit polyclonal antibody to HNF4α
-
货号：
54370 -
别名：
Hepatocyte nuclear factor 4~alpha; HNF~4~alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF~14; Transcription factor HNF~4 -
应用：
WB IHC -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P41235 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit polyclonal antibody to HNF4α
Description |
|---|
Hepatocyte nuclear factor 4α (HNF4α) is a transcription factor that belongs to the steroid hormone receptor superfamily and is enriched in liver. HNF4α, in association with PGC~1α, activates gluconeogenic genes such as phosphoenolpyruvate carboxykinase and glucose~6~phosphatase genes in fasted livers. Conditional knockout of the HNF4α gene in the mouse liver destroys lipid homeostasis and leads to lipid accumulation in the liver and a reduction of serum cholesterol and triglyceride levels. Mutations in HNF4α have been linked to maturity~onset diabetes of the young (MODY). |
Specification |
|
|---|---|
| Aliases | Hepatocyte nuclear factor 4~alpha; HNF~4~alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF~14; Transcription factor HNF~4 |
| Swissprot | P41235 |
| clone | 8A3C10 |
| WB Predicted band size | ~58kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide, corresponding to Human HNF4α. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/1000~1/2000 |
| IHC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54370
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