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Rabbit polyclonal antibody to AIF
-
货号：
54291 -
别名：
AIFM1, AIFM1, AIFM1, Apoptosis inducing factor 1, mitochondrial, Apoptosis inducing factor, Apoptosis inducing factor, mitochondrion associated, 1, Apoptosis~inducing factor 1, CMTX4, COWCK, COXPD6, Harlequin, Hq, mAIF, MGC111425, MGC5706, mitochondrial, Neuropathy, axonal motor~sensory, with deafness and mental retardation, neuropathy, axonal, motor~sensory with deafness and mental retardation (Cowchock syndrome), PDCD 8, PDCD8, Programmed cell death 8 (apoptosis inducing factor), Programmed cell death 8, Programmed cell death 8 isoform 1, Programmed cell death 8 isoform 2, Programmed cell death 8 isoform 3, Programmed cell death protein 8, Programmed cell death protein 8 mitochondrial, Programmed cell death protein 8 mitochondrial precursor, Programmed cell death protein 8 mitochondrial precursor, Striatal apoptosis inducing factor, -
应用：
WB ICC IHC IP FCM -
反应种属：
Human, Mouse, Rat -
抗体类型：
Primary antibody -
Swissprot：
O95831(Human) Q9Z0X1(Mouse) Q9JM53(Rat) -
规格：
-
数量：
-+ -
说明书：
目录价¥1180
Rabbit polyclonal antibody to AIF
Description |
|---|
A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl~2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases 2, 3, and 9, and AIF (apoptosis~inducing factor). AIF has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase~9 from mitochondria. Bcl~2 overexpression has been shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity. |
Specification |
|
|---|---|
| Aliases | AIFM1, AIFM1, AIFM1, Apoptosis inducing factor 1, mitochondrial, Apoptosis inducing factor, Apoptosis inducing factor, mitochondrion associated, 1, Apoptosis~inducing factor 1, CMTX4, COWCK, COXPD6, Harlequin, Hq, mAIF, MGC111425, MGC5706, mitochondrial, Neuropathy, axonal motor~sensory, with deafness and mental retardation, neuropathy, axonal, motor~sensory with deafness and mental retardation (Cowchock syndrome), PDCD 8, PDCD8, Programmed cell death 8 (apoptosis inducing factor), Programmed cell death 8, Programmed cell death 8 isoform 1, Programmed cell death 8 isoform 2, Programmed cell death 8 isoform 3, Programmed cell death protein 8, Programmed cell death protein 8 mitochondrial, Programmed cell death protein 8 mitochondrial precursor, Programmed cell death protein 8 mitochondrial precursor, Striatal apoptosis inducing factor, |
| Swissprot | O95831(Human) Q9Z0X1(Mouse) Q9JM53(Rat) |
| clone | 6F6B7 |
| WB Predicted band size | ~67kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at +4°C after thawing. Aliquot store at ~20°C or ~80°C. Avoid repeated freeze / thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | recombinant protein |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/1000~1/5000 |
| IHC | 1/50~1/200 |
| FCM | 1/50~1/100 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54291
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