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Rabbit polyclonal antibody to Lamin A/C (D230)
-
货号：
54254 -
别名：
Prelamin~A/C; Lamin~A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY~REN~32; LMNA; LMN1; Lamin A; LaminA; Lamin~A; Lamin C; LaminC; Lamin~C -
应用：
WB IHC -
反应种属：
Human,Mouse,Rat -
抗体类型：
Primary antibody -
Swissprot：
P02545 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit polyclonal antibody to Lamin A/C (D230)
Description |
|---|
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization. Lamin A/C is cleaved by caspase~6 and serves as a marker for caspase~6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41~50 kDa) and a small (28 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death. |
Specification |
|
|---|---|
| Aliases | Prelamin~A/C; Lamin~A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY~REN~32; LMNA; LMN1; Lamin A; LaminA; Lamin~A; Lamin C; LaminC; Lamin~C |
| Swissprot | P02545 |
| clone | 9H1A8 |
| WB Predicted band size | ~64,73kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide, corresponding to amino acids 231~280 of Human Lamin A. |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Application |
|
|---|---|
| WB | 1/500~1/1000 |
| IHC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#54254
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