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Western blot (WB) analysis of ZC3H8 pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(20ug) Lane2:Hela whole cell lysate(20ug) Lane3:C6 whole cell lysate(40ug) Lane4:CT26 whole cell lysate(40ug)

Rabbit polyclonal antibody to ZC3H8

货号：
54177
别名：
Zinc finger CCCH domain~containing protein 8; ZC3HDC8
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q8N5P1
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to ZC3H8

Description
Zinc~finger CCCH domain~containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence~specific DNA~binding factor that binds to the 5'~AGGTCTC~3' sequence within the negative cis~acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity). ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Description

Zinc~finger CCCH domain~containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence~specific DNA~binding factor that binds to the 5'~AGGTCTC~3' sequence within the negative cis~acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity). ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specification
Aliases	Zinc finger CCCH domain~containing protein 8; ZC3HDC8
Swissprot	Q8N5P1
clone	1H7B10
WB Predicted band size	~33kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 133~178 of Human ZC3H8.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2