搜索

热搜关键词：
P16
IRAK4
GPC3
MMP9
IL28A
EPCAM
MK167
HAS2

请登录

提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388785

首页 > 产品中心 > 产品详情

Rabbit polyclonal antibody to NF2/Merlin (phospho~S518)

Western blot (WB) analysis of p~NF2 (S518) pAb at 1:500 dilution Lane1:A375 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:The Uterus tissue lysate of Rat(40ug) Lane4:CT26 whole cell lysate(40ug)

Rabbit polyclonal antibody to NF2/Merlin (phospho~S518)

货号：
54160
别名：
Merlin; Moesin~ezrin~radixin~like protein; Neurofibromin~2; Schwannomerlin; Schwannomin; NF2; SCH
产品上架时间：
2024-01-01
应用：
WB IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P35240
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

分享
咨询
收藏

加入购物车

立即购买

Rabbit polyclonal antibody to NF2/Merlin (phospho~S518)

Description
Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.

Description

Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.

Specification
Aliases	Merlin; Moesin~ezrin~radixin~like protein; Neurofibromin~2; Schwannomerlin; Schwannomin; NF2; SCH
Swissprot	P35240
clone	10H4H10
WB Predicted band size	~70kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human Merlin around the phosphorylation site of Serine 518.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2