Rabbit polyclonal antibody to GAP43 (phospho~S41)

GAP~43 (growth associated protein 43, B~50, PP46, calmodulin~binding protein P~57, neuromodulin, neuron growth~associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP~43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron~specific Elav/Hu family member, HuD, interacts with and stabilizes GAP~43 mRNA in developing neurons and leads to increased levels of GAP~43 protein.