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Rabbit polyclonal antibody to JNK1/2/3 (phospho~T183)

Western blot (WB) analysis of p~JNK1/2/3 (T183) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:MCF~7 whole cell lysate(40ug) Lane3:K562 whole cell lysate(20ug) Lane4:The Brain tissue lysate of Rat(40ug) Lane5:The Kidney tissue lysate of Mouse(20ug)

Rabbit polyclonal antibody to JNK1/2/3 (phospho~T183)

货号：
54147
别名：
JNK 46; JNK 55; JNK; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3A; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 8; MAPK 9; MAPK10; MAPK8; MAPK9; MGC50974; Mitogen activated protein kinase 10; Mitogen activated protein kinase 8; Mitogen activated protein kinase 9;
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P45983/P45984/P53779
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to JNK1/2/3 (phospho~T183)

Description
The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras~transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c~Fos, c~Jun and other signaling kinases, including MEKK1 and p38. JNK3 (MK10, MAPK10, PRKM10) is activated by pro~inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c~Jun and ATF2. This is important for AP~1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress~induced).

Description

The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras~transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c~Fos, c~Jun and other signaling kinases, including MEKK1 and p38. JNK3 (MK10, MAPK10, PRKM10) is activated by pro~inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c~Jun and ATF2. This is important for AP~1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress~induced).

Specification
Aliases	JNK 46; JNK 55; JNK; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3A; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 8; MAPK 9; MAPK10; MAPK8; MAPK9; MGC50974; Mitogen activated protein kinase 10; Mitogen activated protein kinase 8; Mitogen activated protein kinase 9;
Swissprot	P45983/P45984/P53779
clone	1A2H8
WB Predicted band size	~54kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Threonine 183.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2