搜索

热搜关键词：
P16
IRAK4
GPC3
MMP9
IL28A
EPCAM
MK167
HAS2

请登录

提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388785

首页 > 产品中心 > 产品详情

Rabbit polyclonal antibody to eIF4E (phospho~S209)

Western blot (WB) analysis of p~eIF4E (S209) pAb at 1:500 dilution Lane1:The Lung tissue lysate of Mouse(40ug) Lane2:The Brain tissue lysate of Rat(40ug) Lane3:3T3~L1 whole cell lysate(40ug) Lane4:C6 whole cell lysate(40ug) Lane5:A2780 whole cell lysate(40ug) Lane6:SK~OVCAR3 whole cell lysate(40ug) Lane7:Panc1 whole cell lysate(20ug)

Rabbit polyclonal antibody to eIF4E (phospho~S209)

货号：
54140
别名：
eIF4E ( phospho S209 ); eIF~4E; eIF4E; mRNA cap~binding protein; eIF~4F 25 kDa subunit; EIF4E; 1977; EIF4E; 133440; P06730; CBP; EIF4EL1; EIF4F; MGC111573;
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P06730
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

分享
咨询
收藏

加入购物车

立即购买

Rabbit polyclonal antibody to eIF4E (phospho~S209)

Description
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.

Description

eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.

Specification
Aliases	eIF4E ( phospho S209 ); eIF~4E; eIF4E; mRNA cap~binding protein; eIF~4F 25 kDa subunit; EIF4E; 1977; EIF4E; 133440; P06730; CBP; EIF4EL1; EIF4F; MGC111573;
Swissprot	P06730
clone	10G3C10
WB Predicted band size	~25kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human eIF4E around the phosphorylation site of Serine 209.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2