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Rabbit polyclonal antibody to EIF4G1 (phospho~S1148)

Western blot (WB) analysis of EIF4G1 (phospho~S1148) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:MCF~7 whole cell lysate(30ug)

Rabbit polyclonal antibody to EIF4G1 (phospho~S1148)

货号：
54100
别名：
Eukaryotic translation initiation factor 4 gamma 1; eIF~4~gamma 1; eIF~4G 1; eIF~4G1; p220; EIF4G1; EIF4F; EIF4G; EIF4GI
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q04637
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to EIF4G1 (phospho~S1148)

Description
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA “cap” during an early step in the initiation of protein synthesis. eIF4A acts as an ATP~dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex .

Description

The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA “cap” during an early step in the initiation of protein synthesis. eIF4A acts as an ATP~dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex .

Specification
Aliases	Eukaryotic translation initiation factor 4 gamma 1; eIF~4~gamma 1; eIF~4G 1; eIF~4G1; p220; EIF4G1; EIF4F; EIF4G; EIF4GI
Swissprot	Q04637
clone	10E10E10
WB Predicted band size	~250kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide corresponding to residues in Human EIF4G1 around the phosphorylation site of S1148.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2