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Rabbit polyclonal antibody to Eg5 (phospho~T926)

Western blot (WB) analysis of p~Eg5 (T926) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(40µg) Lane2:HepG2 whole cell lysate(40µg) Lane3:CT~26 whole cell lysate(40µg) Lane4:C6 whole cell lysate(40µg) Lane5:LOVO whole cell lysate(40µg) Lane6:MCF~7 whole cell lysate(40µg)

Rabbit polyclonal antibody to Eg5 (phospho~T926)

货号：
54094
别名：
Kinesin~like protein KIF11; Kinesin~like protein 1; Kinesin~like spindle protein HKSP; Kinesin~related motor protein Eg5; Thyroid receptor~interacting protein 5; TR~interacting protein 5; TRIP~5; KIF11; EG5; KNSL1; TRIP5
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P52732
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to Eg5 (phospho~T926)

Description
Eg5 (also called kinesin~like protein 11 or Kif11) belongs to the kinesin~like family of motor proteins important in chromosome positioning, centrosome separation, and mitotic spindle formation. Phosphorylation of Eg5 by mitotic kinases regulates its activity by modulating its association with microtubules. Because anti~mitotic chemotherapeutic drugs, such as taxanes, target microtubules and have pleiotropic and sometimes toxic effects, drugs that target microtubule~associated proteins such as Eg5 are currently in development.

Description

Eg5 (also called kinesin~like protein 11 or Kif11) belongs to the kinesin~like family of motor proteins important in chromosome positioning, centrosome separation, and mitotic spindle formation. Phosphorylation of Eg5 by mitotic kinases regulates its activity by modulating its association with microtubules. Because anti~mitotic chemotherapeutic drugs, such as taxanes, target microtubules and have pleiotropic and sometimes toxic effects, drugs that target microtubule~associated proteins such as Eg5 are currently in development.

Specification
Aliases	Kinesin~like protein KIF11; Kinesin~like protein 1; Kinesin~like spindle protein HKSP; Kinesin~related motor protein Eg5; Thyroid receptor~interacting protein 5; TR~interacting protein 5; TRIP~5; KIF11; EG5; KNSL1; TRIP5
Swissprot	P52732
clone	9A6C3
WB Predicted band size	~120kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human Eg5 around the phosphorylation site of Threonine 926
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2