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Rabbit polyclonal antibody to HSP27 (phospho~S15)

Western blot (WB) analysis of HSP27 (phospho~S15) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:HEK293T incubated at 42ºC for 1 hour whole cell lysate

Rabbit polyclonal antibody to HSP27 (phospho~S15)

货号：
54018
别名：
Heat shock protein beta~1; HspB1; 28 kDa heat shock protein; Estrogen~regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress~responsive protein 27; SRP27; HSPB1; HSP27; HSP28
产品上架时间：
2024-01-01
应用：
WB IHC IP
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04792
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥2180

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Rabbit polyclonal antibody to HSP27 (phospho~S15)

Description
Hsp27, also referred to as the Estrogen~Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a~crystalline lens protein. Because of the estrogen~responsive nature of Hsp27, this protein has been studied extensively in human estrogen~responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.

Description

Hsp27, also referred to as the Estrogen~Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a~crystalline lens protein. Because of the estrogen~responsive nature of Hsp27, this protein has been studied extensively in human estrogen~responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.

Specification
Aliases	Heat shock protein beta~1; HspB1; 28 kDa heat shock protein; Estrogen~regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress~responsive protein 27; SRP27; HSPB1; HSP27; HSP28
Swissprot	P04792
clone	7F10H7
WB Predicted band size	~27kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic phosphopeptide derived from human HSP27 around the phosphorylation site of Serine 15.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2