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Rabbit polyclonal antibody to CrkL (phospho~Y207)

Western blot (WB) analysis of p~CrkL (Y207) pAb at 1:500 dilution Lane1:MCF~7 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:PMVEC whole cell lysate(40ug) Lane4:CT26 whole cell lysate(40ug) Lane5:SGC7901 whole cell lysate(40ug)

Rabbit polyclonal antibody to CrkL (phospho~Y207)

货号：
54003
别名：
Crk L; Crk like protein; Crk~like protein; Crkl; Crkol; Oncogene CrkL;
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P46109
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to CrkL (phospho~Y207)

Description
Crk, is a transformation~specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk~L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk~L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.

Description

Crk, is a transformation~specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk~L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk~L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.

Specification
Aliases	Crk L; Crk like protein; Crk~like protein; Crkl; Crkol; Oncogene CrkL;
Swissprot	P46109
clone	5F8A10
WB Predicted band size	~39kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic phosphopeptide derived from human CrkL around the phosphorylation site of Tyrosine 207.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2