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Rabbit polyclonal antibody to SFRS15 (V641)

Western blot (WB) analysis of SFRS15 (V641) pAb at 1:1000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(20ug)

Rabbit polyclonal antibody to SFRS15 (V641)

货号：
53983
别名：
Splicing factor, arginine/serine~rich 15; CTD~binding SR~like protein RA4; SR~related and CTD~associated factor 4; SCAF4; KIAA1172; SFRS15
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O95104
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to SFRS15 (V641)

Description
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR~rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration~dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine~rich 15 (SFRS15), also designated CTD~binding SR~like protein RA4, contains one RRM and one SR~rich domains. SFRS15 interacts with C~terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre~mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

Description

The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR~rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration~dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine~rich 15 (SFRS15), also designated CTD~binding SR~like protein RA4, contains one RRM and one SR~rich domains. SFRS15 interacts with C~terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre~mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

Specification
Aliases	Splicing factor, arginine/serine~rich 15; CTD~binding SR~like protein RA4; SR~related and CTD~associated factor 4; SCAF4; KIAA1172; SFRS15
Swissprot	O95104
clone	5E1F10
WB Predicted band size	~170kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 611~660 of Human SFRS15.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2