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Rabbit polyclonal antibody to MDFI (P134)

Western blot (WB) analysis of MDFI (P134) pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug) Lane4:HCT116 whole cell lysate(40ug) Lane5:C6 whole cell lysate(40ug) Lane6:3T3~L1 whole cell lysate(40ug)

Rabbit polyclonal antibody to MDFI (P134)

货号：
53972
别名：
MyoD family inhibitor; Myogenic repressor I~mf; MDFI
产品上架时间：
2024-01-01
应用：
WB IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q99750
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to MDFI (P134)

Description
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I~mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA~binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Description

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I~mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA~binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Specification
Aliases	MyoD family inhibitor; Myogenic repressor I~mf; MDFI
Swissprot	Q99750
clone	8D6A8
WB Predicted band size	~25kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 100~146 of Human MDFI.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2