Rabbit polyclonal antibody to HLA~H (I104)

The protein encoded by this gene is a membrane protein that is similar to MHC class I~type proteins and associates with beta2~microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full~length nature has not been determined