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Rabbit polyclonal antibody to ACTR~IIA (H59)

Western blot (WB) analysis of ACTR~IIA (H59) pAb at 1:500 dilution Lane1:AML~12 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)

Rabbit polyclonal antibody to ACTR~IIA (H59)

货号：
53922
别名：
Activin receptor type~2A; EC=2.7.11.30; Activin receptor type IIA; ACTR~IIA; ACTRIIA; ACVR2A; ACVR2
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P27037
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to ACTR~IIA (H59)

Description
Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR~IA (also designated ACVRI and ALK~2) or ACTR~IB (also designated ALK~4 and SKR2), and a type II receptor, ACTR~IIA (ACVR2A) or ACTR~IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.

Description

Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR~IA (also designated ACVRI and ALK~2) or ACTR~IB (also designated ALK~4 and SKR2), and a type II receptor, ACTR~IIA (ACVR2A) or ACTR~IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.

Specification
Aliases	Activin receptor type~2A; EC=2.7.11.30; Activin receptor type IIA; ACTR~IIA; ACTRIIA; ACVR2A; ACVR2
Swissprot	P27037
clone	8E3H9
WB Predicted band size	~58kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 30~80 of Human ACTR~IIA.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2