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Rabbit polyclonal antibody to eIF2α (I45)

Western blot (WB) analysis of eIF2α (I45) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:NIH~3T3 whole cell lysate(40ug) Lane5:PC12 whole cell lysate(40ug)

Rabbit polyclonal antibody to eIF2α (I45)

货号：
53917
别名：
Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF~2~alpha; eIF~2A; eIF~2alpha; EIF2A; EIF2S1
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P05198
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to eIF2α (I45)

Description
eIF2α, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP~dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2α controls the rate of tRNA translation. When eIF2α is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2α is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.

Description

eIF2α, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP~dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2α controls the rate of tRNA translation. When eIF2α is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2α is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.

Specification
Aliases	Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF~2~alpha; eIF~2A; eIF~2alpha; EIF2A; EIF2S1
Swissprot	P05198
clone	1C2E6
WB Predicted band size	~38kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 11~60 of Human eIF2α.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2