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Rabbit polyclonal antibody to Op18 (V31)

Western blot (WB) analysis of Op18 (V31) pAb at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:K562 whole cell lysate(10ug) Lane3:The Brain tissue lysate of Rat(5ug)

Rabbit polyclonal antibody to Op18 (V31)

货号：
53911
别名：
Stathmin; Leukemia~associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P16949
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to Op18 (V31)

Description
Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin~associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phosphorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Description

Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin~associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phosphorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Specification
Aliases	Stathmin; Leukemia~associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18
Swissprot	P16949
clone	6B8E6
WB Predicted band size	~19kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to the N~terminus of Human Op18.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2