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Rabbit polyclonal antibody to NCoA~3 (S587)

Western blot (WB) analysis of NCoA~3 (S587) pAb at 1:500 dilution Lane1:H9C2 whole cell lysate(40ug) Lane2:AML~12 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:Panc1 whole cell lysate(40ug) Lane5:MCF~7 whole cell lysate(40ug)

Rabbit polyclonal antibody to NCoA~3 (S587)

货号：
53884
别名：
Nuclear receptor coactivator 3; NCoA~3; EC=2.3.1.48; ACTR; Amplified in breast cancer 1 protein; AIB~1; CBP~interacting protein; pCIP; Class E basic helix~loop~helix protein 42; bHLHe42; Receptor~associated coactivator 3; RAC~3; Steroid receptor coactivator protein 3; SRC~3; Thyroid hormone receptor activator molecule 1; TRAM~1; AIB1; BHLHE42; RAC3; TRAM1; NCOA3
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y6Q9
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to NCoA~3 (S587)

Description
Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone~responsive elements. This family includes GRIP1 (for GR interacting protein 1), also designated NCoA~2 or TIF~2; SRC~1 (for steroid receptor coactivator~1), also designated NCoA~1; and NCoA~3, also designated RAC3, ACTR, AIB~1 (for amplified in breast cancer) and p/CIP (for p300/CBP/co~integrator protein), which displays elevated expression in estrogen receptor positive ovarian and breast cancers and is required for the transcriptional activation of p300/CBP~dependent transcription factors.

Description

Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone~responsive elements. This family includes GRIP1 (for GR interacting protein 1), also designated NCoA~2 or TIF~2; SRC~1 (for steroid receptor coactivator~1), also designated NCoA~1; and NCoA~3, also designated RAC3, ACTR, AIB~1 (for amplified in breast cancer) and p/CIP (for p300/CBP/co~integrator protein), which displays elevated expression in estrogen receptor positive ovarian and breast cancers and is required for the transcriptional activation of p300/CBP~dependent transcription factors.

Specification
Aliases	Nuclear receptor coactivator 3; NCoA~3; EC=2.3.1.48; ACTR; Amplified in breast cancer 1 protein; AIB~1; CBP~interacting protein; pCIP; Class E basic helix~loop~helix protein 42; bHLHe42; Receptor~associated coactivator 3; RAC~3; Steroid receptor coactivator protein 3; SRC~3; Thyroid hormone receptor activator molecule 1; TRAM~1; AIB1; BHLHE42; RAC3; TRAM1; NCOA3
Swissprot	Q9Y6Q9
clone	9D3E3
WB Predicted band size	~155kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 558~600 of Human NCoA~3.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2