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Rabbit polyclonal antibody to CHP2 (M136)

Western blot (WB) analysis of CHP2 (M136) Antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:MG63 whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:AML~12 whole cell lysate(40ug)

Rabbit polyclonal antibody to CHP2 (M136)

货号：
53822
别名：
Serine/threonine~protein kinase MARK1; MAP/microtubule affinity~regulating kinase 1; PAR1 homolog c; Par~1c; Par1c; MARK1; KIAA1477; MARK; Serine/threonine~protein kinase MARK2 ; ELKL motif kinase 1; EMK~1; MAP/microtubule affinity~regulating kinase 2; PAR1 homolog; PAR1 homolog b; Par~1b; Par1b; MARK2; EMK1; MAP/microtubule affinity~regulating kinase 3; C~TAK1; cTAK1; Cdc25C~associated protein kinase 1; ELKL motif kinase 2; EMK~2; Protein kinase STK10; Ser/Thr protein kinase PAR~1; Par~1a; Serine/threonine~protein kinase p78; MARK3; CTAK1; EMK2; MAP/microtubule affinity~regulating kinase 4; MAP/microtubule affinity~regulating kinase~like 1; MARK4; KIAA1860; MARKL1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O43745
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to CHP2 (M136)

Description
Calcineurin B homologous protein 2, functions as an integral cofactor in cell pH regulation by controlling plasma membrane~type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum~independent manner, thus increasing pH and protecting cells from serum deprivation~induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium~dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

Description

Calcineurin B homologous protein 2, functions as an integral cofactor in cell pH regulation by controlling plasma membrane~type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum~independent manner, thus increasing pH and protecting cells from serum deprivation~induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium~dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

Specification
Aliases	Serine/threonine~protein kinase MARK1; MAP/microtubule affinity~regulating kinase 1; PAR1 homolog c; Par~1c; Par1c; MARK1; KIAA1477; MARK; Serine/threonine~protein kinase MARK2 ; ELKL motif kinase 1; EMK~1; MAP/microtubule affinity~regulating kinase 2; PAR1 homolog; PAR1 homolog b; Par~1b; Par1b; MARK2; EMK1; MAP/microtubule affinity~regulating kinase 3; C~TAK1; cTAK1; Cdc25C~associated protein kinase 1; ELKL motif kinase 2; EMK~2; Protein kinase STK10; Ser/Thr protein kinase PAR~1; Par~1a; Serine/threonine~protein kinase p78; MARK3; CTAK1; EMK2; MAP/microtubule affinity~regulating kinase 4; MAP/microtubule affinity~regulating kinase~like 1; MARK4; KIAA1860; MARKL1
Swissprot	O43745
clone	8H2H8
WB Predicted band size	~23kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 122~182 of Human MARK1/2/3/4.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2