搜索

热搜关键词：
P16
IRAK4
GPC3
MMP9
IL28A
EPCAM
MK167
HAS2

请登录

提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388785

首页 > 产品中心 > 产品详情

Rabbit polyclonal antibody to PAK4/5/6 (V469)

Western blot (WB) analysis of PAK4/5/6 (V469) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(20ug) Lane2:MCF~7 whole cell lysate(20ug) Lane3:PC3 whole cell lysate(20ug) Lane4:The Testis tissue lysate of Mouse(40ug) Lane5:The Testis tissue lysate of Rat(40ug)

Rabbit polyclonal antibody to PAK4/5/6 (V469)

货号：
53818
别名：
Serine/threonine~protein kinase PAK 4; p21~activated kinase 4; PAK~4; PAK4; KIAA1142; Serine/threonine~protein kinase PAK 6; PAK~5; p21~activated kinase 6; PAK~6; PAK6; PAK5; Serine/threonine~protein kinase PAK 7; p21~activated kinase 5; p21~activated kinase 7; PAK~7; PAK7; KIAA1264
产品上架时间：
2024-01-01
应用：
WB IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O96013/Q9NQU5/Q9P286
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

分享
咨询
收藏

加入购物车

立即购买

Rabbit polyclonal antibody to PAK4/5/6 (V469)

Description
PAK4 is highly expressed in prostate, testis and colon. PAK4 interacts tightly with GTP~bound but not GDP~bound CDC42 and weakly with RAC. PAK4 phosphorylates and autophosphorylates and also activates the JNK pathway. PAK5, a member of the PAK family of protein kinases contains a CDC42/Rac1 interactive binding (CRIB) motif at the N~terminus and a Ste20~like kinase domain at the C~terminus. PAK5 preferentially binds to CDC42 in the presence of GTP and the CRIB motif is essential for this interaction.PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone~dependent transcription factor that is important for male sexual differentiation and development, in response to androgen.

Description

PAK4 is highly expressed in prostate, testis and colon. PAK4 interacts tightly with GTP~bound but not GDP~bound CDC42 and weakly with RAC. PAK4 phosphorylates and autophosphorylates and also activates the JNK pathway. PAK5, a member of the PAK family of protein kinases contains a CDC42/Rac1 interactive binding (CRIB) motif at the N~terminus and a Ste20~like kinase domain at the C~terminus. PAK5 preferentially binds to CDC42 in the presence of GTP and the CRIB motif is essential for this interaction.PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone~dependent transcription factor that is important for male sexual differentiation and development, in response to androgen.

Specification
Aliases	Serine/threonine~protein kinase PAK 4; p21~activated kinase 4; PAK~4; PAK4; KIAA1142; Serine/threonine~protein kinase PAK 6; PAK~5; p21~activated kinase 6; PAK~6; PAK6; PAK5; Serine/threonine~protein kinase PAK 7; p21~activated kinase 5; p21~activated kinase 7; PAK~7; PAK7; KIAA1264
Swissprot	O96013/Q9NQU5/Q9P286
clone	7C2H6
WB Predicted band size	~64kDa(PAK4),80kDa(PAK5),75kDa(PAK6)
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 441~490 of Human PAK4.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2