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Rabbit polyclonal antibody to mAChR M4 (P277)

Western blot (WB) analysis of mAChR M4 (P277) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(40ug) Lane2:MCF~7 whole cell lysate(40ug) Lane3:K562 whole cell lysate(40ug) Lane4:C6 whole cell lysate(40ug) Lane5:SP2/0 whole cell lysate(40ug)

Rabbit polyclonal antibody to mAChR M4 (P277)

货号：
53816
别名：
Muscarinic acetylcholine receptor M4,CHRM4
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P08173
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to mAChR M4 (P277)

Description
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G~proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

Description

The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G~proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

Specification
Aliases	Muscarinic acetylcholine receptor M4,CHRM4
Swissprot	P08173
clone	3B4F2
WB Predicted band size	~53kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 241~290 of Human mAChR M4.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2