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Rabbit polyclonal antibody to PI3K p55γ (Y463)

Western blot (WB) analysis of PI3K p85α/p55γ (Y463) pAb at 1:500 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:The Brain tissue lysate of Mouse(40ug) Lane4:The Testis tissue lysate of Rat(40ug)

Rabbit polyclonal antibody to PI3K p55γ (Y463)

货号：
53780
别名：
Phosphatidylinositol 3~kinase regulatory subunit alpha; PI3~kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns~3~kinase regulatory subunit alpha; Phosphatidylinositol 3~kinase 85 kDa regulatory subunit alpha; PI3~kinase subunit p85~alpha; PtdIns~3~kinase regulatory subunit p85~alpha; PIK3R1; GRB1; Phosphatidylinositol 3~kinase regulatory subunit gamma; PI3~kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns~3~kinase regulatory subunit gamma; Phosphatidylinositol 3~kinase 55 kDa regulatory subunit gamma; PI3~kinase subunit p55~gamma; PtdIns~3~kinase regulatory subunit p55~gamma; p55PIK; PIK3R3
产品上架时间：
2024-01-01
应用：
WB IHC IF IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q92569
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to PI3K p55γ (Y463)

Description
The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5~triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin~stimulated increase in glucose uptake and glycogen synthesis in insulin~sensitive tissues.

Description

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5~triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin~stimulated increase in glucose uptake and glycogen synthesis in insulin~sensitive tissues.

Specification
Aliases	Phosphatidylinositol 3~kinase regulatory subunit alpha; PI3~kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns~3~kinase regulatory subunit alpha; Phosphatidylinositol 3~kinase 85 kDa regulatory subunit alpha; PI3~kinase subunit p85~alpha; PtdIns~3~kinase regulatory subunit p85~alpha; PIK3R1; GRB1; Phosphatidylinositol 3~kinase regulatory subunit gamma; PI3~kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns~3~kinase regulatory subunit gamma; Phosphatidylinositol 3~kinase 55 kDa regulatory subunit gamma; PI3~kinase subunit p55~gamma; PtdIns~3~kinase regulatory subunit p55~gamma; p55PIK; PIK3R3
Swissprot	Q92569
clone	10A1C10
WB Predicted band size	~55kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 430~480 of Human PI3K p85α.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2