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Rabbit polyclonal antibody to PIM1 (I302)

Western blot (WB) analysis of PIM1 (I302) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

Rabbit polyclonal antibody to PIM1 (I302)

货号：
53776
别名：
Serine/threonine~protein kinase pim~1; Pim1; Pim~1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P11309
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1280

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Rabbit polyclonal antibody to PIM1 (I302)

Description
Pim~1 is a serine/threonine kinase that cooperates with c~Myc in lymphoid cell transformation. The expression of Pim~1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim~1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL~2 stimulation. Pim~1 also plays a role in T cell differentiation, and it has been shown to stimulate c~Myc~mediated apoptosis upstream of caspase~3~like proteases.

Description

Pim~1 is a serine/threonine kinase that cooperates with c~Myc in lymphoid cell transformation. The expression of Pim~1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim~1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL~2 stimulation. Pim~1 also plays a role in T cell differentiation, and it has been shown to stimulate c~Myc~mediated apoptosis upstream of caspase~3~like proteases.

Specification
Aliases	Serine/threonine~protein kinase pim~1; Pim1; Pim~1
Swissprot	P11309
clone	3H10B3
WB Predicted band size	~45kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 271~320 of Human Pim~1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2