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Rabbit polyclonal antibody to XRCC5 (S462)

Western blot (WB) analysis of XRCC5 (S462) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:A549 whole cell lysate(20ug) Lane3:SK~OVCAR3 whole cell lysate(20ug) Lane4:The Testis tissue lysate of Mouse(40ug) Lane5:The Testis tissue lysate of Rat(40ug)

Rabbit polyclonal antibody to XRCC5 (S462)

货号：
53748
别名：
X~ray repair cross~complementing protein 5; 86 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 2; ATP~dependent DNA helicase II 80 kDa subunit; CTC box~binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Ku~80; Ku~86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in Chinese hamster cells 5 (double~strand~break rejoining); XRCC5; G22P2
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P13010
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to XRCC5 (S462)

Description
XRCC5 encoded by this gene is the 80~kilodalton subunit of the Ku heterodimer protein which is also known as ATP~dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA~binding component of the DNA~dependent protein kinase, and it functions together with the DNA ligase IV~XRCC4 complex in the repair of DNA double~strand break by non~homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs~6, a mutant defective in DNA double~strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Description

XRCC5 encoded by this gene is the 80~kilodalton subunit of the Ku heterodimer protein which is also known as ATP~dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA~binding component of the DNA~dependent protein kinase, and it functions together with the DNA ligase IV~XRCC4 complex in the repair of DNA double~strand break by non~homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs~6, a mutant defective in DNA double~strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Specification
Aliases	X~ray repair cross~complementing protein 5; 86 kDa subunit of Ku antigen; ATP~dependent DNA helicase 2 subunit 2; ATP~dependent DNA helicase II 80 kDa subunit; CTC box~binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Ku~80; Ku~86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid~lupus autoantigen; TLAA; X~ray repair complementing defective repair in Chinese hamster cells 5 (double~strand~break rejoining); XRCC5; G22P2
Swissprot	P13010
clone	7F3B5
WB Predicted band size	~82kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide, corresponding to amino acids 450~480 of Human XRCC5.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2