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Rabbit polyclonal antibody to Spindlin~1 (H139)

Western blot (WB) analysis of Spindlin~1 (H139) pAb at 1:500 dilution Lane1:SK~OVCAR3 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:The Ovarian tissue lysate of Rat(40ug) Lane4:The Testis tissue lysate of Mouse(40ug)

Rabbit polyclonal antibody to Spindlin~1 (H139)

货号：
53743
别名：
OCR; Ovarian cancer~related protein; SPIN; Spin1; SPIN1; Spindlin 1;
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y657
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to Spindlin~1 (H139)

Description
SPIN1 (spindlin 1), also known as SPIN or ovarian cancer~related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell~cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell~cycle~dependent fashion. A meiotic spindle~binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Description

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer~related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell~cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell~cycle~dependent fashion. A meiotic spindle~binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Specification
Aliases	OCR; Ovarian cancer~related protein; SPIN; Spin1; SPIN1; Spindlin 1;
Swissprot	Q9Y657
clone	5A6C10
WB Predicted band size	~30kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 110~156 of Human Spindlin~1.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2