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Rabbit polyclonal antibody to DPF2 (E174)

Western blot (WB) analysis of DPF2 (E174) polyclonal antibody at 1:1000 dilution Lane1:THP~1 whole cell lysate(37ug) Lane2:MCF~7 whole cell lysate(48ug) Lane3:RAW264.7 whole cell lysate(57ug) Lane4:NIH3T3 whole cell lysate(48ug) Lane5:H9C2 whole cell lysate(37ug)

Rabbit polyclonal antibody to DPF2 (E174)

货号：
53740
别名：
Apoptosis response zinc finger protein; BAF45D; BRG1~associated factor 45D; D4; D4 zinc and double PHD fingers family 2; double PHD fingers family 2; DPF 2; DPF2; MGC10180; Protein requiem; REQ; REQU; Requiem; Requiem apoptosis response zinc finger; UBI D4; ubi~d4; UBID 4; UBID4; zinc and double PHD fingers family 2; Zinc finger protein ubi d4;
产品上架时间：
2024-01-01
应用：
WB IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q92785
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to DPF2 (E174)

Description
DPF2 (D4, zinc and double PHD fingers family 2), also known as REQ (Requiem), UBID4 or ubi~d4, is a 391 amino acid protein that is a member of the D4 domain family. DPF2, a ubiquitously expressed protein, localizes to the nucleus and contains one C2H2~ and two PHD~type zinc finger motifs. DPF2 may function as a transcription factor that is necessary for apoptosis and may also play a role in the development and maturation of lymphoid cells. It is thought that, during apoptosis, DPF2 activity is inhibited by LRF (Leukemia/lymphoma~related factor), which is upregulated by integrin. This suggests that DPF2 may be a potential target for future cancer therapies that induce apoptosis in leukemia cells. Alternative splicing of this gene generates multiple isoforms lacking certain domain.

Description

DPF2 (D4, zinc and double PHD fingers family 2), also known as REQ (Requiem), UBID4 or ubi~d4, is a 391 amino acid protein that is a member of the D4 domain family. DPF2, a ubiquitously expressed protein, localizes to the nucleus and contains one C2H2~ and two PHD~type zinc finger motifs. DPF2 may function as a transcription factor that is necessary for apoptosis and may also play a role in the development and maturation of lymphoid cells. It is thought that, during apoptosis, DPF2 activity is inhibited by LRF (Leukemia/lymphoma~related factor), which is upregulated by integrin. This suggests that DPF2 may be a potential target for future cancer therapies that induce apoptosis in leukemia cells. Alternative splicing of this gene generates multiple isoforms lacking certain domain.

Specification
Aliases	Apoptosis response zinc finger protein; BAF45D; BRG1~associated factor 45D; D4; D4 zinc and double PHD fingers family 2; double PHD fingers family 2; DPF 2; DPF2; MGC10180; Protein requiem; REQ; REQU; Requiem; Requiem apoptosis response zinc finger; UBI D4; ubi~d4; UBID 4; UBID4; zinc and double PHD fingers family 2; Zinc finger protein ubi d4;
Swissprot	Q92785
clone	10B7F10
WB Predicted band size	~44kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 140~188 of Human DPF2.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2