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Rabbit polyclonal antibody to HM74 (T327)

Western blot (WB) analysis of GPR109B pAb at 1:500 dilution Lane1:PMVEC whole cell lysate(40ug) Lane2:SP2/0 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:Myla2059 whole cell lysate(40ug) Lane5:MCF~7 whole cell lysate(40ug)

Rabbit polyclonal antibody to HM74 (T327)

货号：
53732
别名：
Hydroxycarboxylic acid receptor 3; G~protein coupled receptor 109B; G~protein coupled receptor HM74; G~protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2; HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 2; G~protein coupled receptor 109A; G~protein coupled receptor HM74A; Niacin receptor 1; Nicotinic acid receptor; HCAR2; GPR109A; HCA2; HM74A; NIACR1
产品上架时间：
2024-01-01
应用：
WB IHC IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P49019/Q8TDS4
规格：

50ul
100ul
数量：

-

+
说明书：

目录价¥1180

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Rabbit polyclonal antibody to HM74 (T327)

Description
HM74, also known as PUMAG or Puma~g, is a member of the G protein coupled receptor (GPCR) superfamily. In humans, HM74 is encoded by two different genes (GPR109A and GPR109B) that produce proteins, namely HM74A and HM74 (or HM74B), which are 96% homologous. In mice and rats, only one gene encodes the HM74 protein (Gpr109a). HM74 is a G(i) protein~coupled receptor that mediates the metabolic effects of nicotinic acid. Localizing to the cell membrane, HM74 is highly expressed in adipocytes, immune cells and spleen. Like all members of the GPCR superfamily, HM74 contains seven transmembrane domains. HM74 lacks the N~linked glycosylation sites near the N~terminus that are present in other GPCR family members.

Description

HM74, also known as PUMAG or Puma~g, is a member of the G protein coupled receptor (GPCR) superfamily. In humans, HM74 is encoded by two different genes (GPR109A and GPR109B) that produce proteins, namely HM74A and HM74 (or HM74B), which are 96% homologous. In mice and rats, only one gene encodes the HM74 protein (Gpr109a). HM74 is a G(i) protein~coupled receptor that mediates the metabolic effects of nicotinic acid. Localizing to the cell membrane, HM74 is highly expressed in adipocytes, immune cells and spleen. Like all members of the GPCR superfamily, HM74 contains seven transmembrane domains. HM74 lacks the N~linked glycosylation sites near the N~terminus that are present in other GPCR family members.

Specification
Aliases	Hydroxycarboxylic acid receptor 3; G~protein coupled receptor 109B; G~protein coupled receptor HM74; G~protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2; HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 2; G~protein coupled receptor 109A; G~protein coupled receptor HM74A; Niacin receptor 1; Nicotinic acid receptor; HCAR2; GPR109A; HCA2; HM74A; NIACR1
Swissprot	P49019/Q8TDS4
clone	8D2A8
WB Predicted band size	~45kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide, corresponding to amino acids 300~350 of Human HM74.
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2